Seroprevalence of Poliovirus Types 1, 2, and 3 Among Children Aged 6-11 Months: Variations Across Survey Rounds in High-Risk Areas of Pakistan.

ABSTRACT: Background: The current polio epidemiology in Pakistan poses a unique challenge for global eradication, with polio transmission dynamics influenced by regional variations in immunity and disparities in immunization coverage. This study assesses the immunity level for all three poliovirus types among children aged 6-11 months in polio high-risk regions of Pakistan. Methods: Four consecutive rounds of cross-sectional serological surveys were conducted in polio high-risk areas of Pakistan between November 2016 and October 2023. Twelve high-risk areas were covered in the first three rounds of the survey, while 44 high-risk areas were covered in the fourth round. 25 clusters from each geographical stratum were selected utilizing probability proportional to size. Results: Ac

SUBMITTER: Hussain I 

PROVIDER: S-EPMC12568277 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature