Cognitive and mental health significantly contribute to disability in people ageing with HIV in Asia: an observational case-control study.

ABSTRACT:

Introduction

Disability disproportionally impacts people living with HIV (PLWH). The burden and determinants of disability among PLWH in Asia have not been well studied.

Methods

We conducted a multi-country observational cross-sectional study in five cities in Asia involving PLWH and age- and sex-matched controls living without HIV from March 2020 to November 2023. We compared the prevalence of disability (measured by World Health Organization Disability Assessment Schedule 2.0, WHODAS 2.0) between PLWH and controls, and determined the association between living with HIV and disability using multivariable logistic regression and mediation analysis.

Results

A total of 1004 PLWH and 416 age- and sex-matched controls were enrolled. PLWH (mean age 53.6 ± 10.3 years, 84.4%

SUBMITTER: Lui G 

PROVIDER: S-EPMC12568376 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature