Serum creatinine-to-albumin ratio as a prognostic marker for short- and long-term mortality in critically ill stroke patients: a MIMIC-IV study.

ABSTRACT:

Introduction

Stroke remains a leading cause of mortality and disability worldwide, with critically ill patients facing particularly poor outcomes. Existing prognostic markers often fail to capture the full spectrum of metabolic and nutritional disturbances in stroke. The serum creatinine-to-albumin ratio (sCAR), reflecting renal function and nutritional status, may offer improved mortality prediction for the intensive care unit (ICU)-admitted stroke patients.

Methods

This retrospective cohort study used the MIMIC-IV database (v2.2) to analyze 2,819 adult stroke patients admitted to the ICU. Patients were stratified into low- and high-sCAR groups based on an optimal cutoff of 0.419. Predictive performance was assessed using Cox regression, Kaplan-Meier survival analysis, and

SUBMITTER: Sun D 

PROVIDER: S-EPMC12568402 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature