Effectiveness and safety of acupuncture for Parkinson's disease anxiety: a systematic review and meta-analysis.

ABSTRACT:

Background

Individuals with Parkinson's disease (PD) commonly experience anxiety, with a prevalence of 31%. This study systematically evaluates the efficacy and safety of acupuncture for anxiety related to PD.

Method

Nine databases were searched for randomized controlled trials (RCTs) published from inception to August 24, 2025. RCTs comparing acupuncture and moxibustion treatments (with or without other therapies, e.g., western medicine, routine care, sham acupuncture) to other therapies alone for managing PD anxiety were included. Data were analyzed using the R software (version 4.5.1). In accordance with PRISMA-2020 guidelines, two reviewers independently extracted data and assessed the risk of bias using the Cochrane risk of bias tool (ROB 2.0). The certainty of the evid

SUBMITTER: Chen L 

PROVIDER: S-EPMC12568604 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature