Associations of white matter hyperintensity with frailty, sarcopenia, and nutritional risk: an analysis of an acute ischemic stroke patient database.

ABSTRACT:

Introduction

White matter hyperintensity (WMH), frailty, sarcopenia, and nutritional risk are prevalent and critical factors in geriatric care. This study aimed to investigate the associations between WMH and frailty, sarcopenia, and nutritional risk status using data derived from an acute ischemic stroke (AIS) hospitalization database.

Methods

Images of brain magnetic resonance imaging were reviewed for patients aged ≥60 years who were hospitalized for AIS. WMH was classified into deep white matter hyperintensity (DWMH) and periventricular hyperintensity (PVH) and graded on a scale from 0 to 3 using the Fazekas scale. Frailty was assessed on the basis of the frailty screening index derived from the interview data. Sarcopenia was diagnosed based on grip strength measured on

SUBMITTER: Akimoto T 

PROVIDER: S-EPMC12568660 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature