Accuracy, repeatability, reproducibility and reference ranges of primary sclerosing cholangitis specific biomarkers from quantitative MRCP.

ABSTRACT:

Purpose

To assess the repeatability and reproducibility of quantitative MRCP-derived metrics generated from MRCP + software, designed for assessing biliary tree health.

Methods

Metric accuracy was assessed using a 3D-printed phantom containing 20 tubes with sinusoidally-varying diameters, simulating strictures and dilatations along ducts. Data from 80 participants (60 healthy volunteers and 20 with liver disease) was analysed in total. Repeatability and reproducibility of the quantitative metrics were assessed on Siemens, GE and Philips scanners at both 1.5T and 3T. All subjects were scanned on a Siemens Prisma 3T scanner which acted as the reference scanner. A subset of these participants also underwent scanning on the remaining scanners. Data from healthy volunteers was us

SUBMITTER: Harisinghani M 

PROVIDER: S-EPMC12568806 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature