Prevalence, clinical characteristics, and hospital course of systemic sclerosis-associated pseudo-obstruction.

ABSTRACT:

Objective

Gastrointestinal involvement is almost universal in patients with systemic sclerosis (SSc). Enteric dysmotility, at its most severe, can present with pseudo-obstruction. In this study, we aimed to quantify the prevalence of SSc pseudo-obstruction and evaluate risk factors for its development. In a subgroup of patients requiring admission to hospital for acute episodes of pseudo-obstruction, we evaluated the clinical course and treatments administered.

Methods

Using data from 1969 Australian Scleroderma Cohort Study (ASCS) participants, we performed multivariable logistic regression analysis to identify SSc-specific risk factors for pseudo-obstruction. Descriptive statistics were used to examine the clinical course of patients admitted with pseudo-obstruction at a s

SUBMITTER: Ross L 

PROVIDER: S-EPMC12568857 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature