Association between hemoglobin glycation index and mortality in surgical ICU patients.

ABSTRACT: The hemoglobin glycation index (HGI) is a promising marker for assessing glycemic control and outcomes in critically ill patients, but its prognostic value in Trauma/Surgical Intensive Care Units (TSICU/SICU) remains unclear. This study investigates the predictive value of HGI in relation to mortality. This retrospective analysis used data from the Medical Information Mart for Intensive Care IV (MIMIC-IV) database, a publicly available critical care database, focusing on TSICU/SICU patients. HGI was calculated as the difference between observed and predicted HbA1c levels. Associations between HGI quartiles and 28-day and 360-day mortality were assessed using Kaplan-Meier survival analysis, multivariate Cox regression, and restricted cubic spline (RCS) models. A stacked ensemble machine lea

SUBMITTER: Ge Y 

PROVIDER: S-EPMC12569067 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature