Magnetic reduced graphene oxide aerogel decorated silver nanoparticles towards efficient recognition of doxorubicin in patients' blood plasma.

ABSTRACT: Doxorubicin (DOX), a potent anticancer drug, requires sensitive and precise detection due to its narrow therapeutic window. In this study, a novel electrochemical sensor was developed by electrodepositing silver nanoprisms (AgNPrs), Fe₃O₄ nanoparticles, and reduced graphene oxide aerogel (rGOA) on a glassy carbon electrode (GCE). The cyclic voltammetry technique was utilized for electrodeposition of Fe₃O₄@rGOA/AgNPrs nanocomposite within a potential range of - 1.0 to + 1.0 V. The Fe₃O₄@rGOA/AgNPrs-modified GCE probe was optimized for the detection and quantification of DOX in human plasma samples. At an optimized pH of 6, DOX exhibited distinct redox behavior on the modified electrode. Differential pulse voltammetry was empl

SUBMITTER: Gheybalizadeh H 

PROVIDER: S-EPMC12569179 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature