Exploring the correlation between eosinophils with clinical risk of severe pneumonia based on MIMIC-IV data.

ABSTRACT: Respiratory tract infections in pneumonia patients can rapidly progress to severe pneumonia (SP). However, the clinical relationship between eosinophils (EOS) and SP prognosis remains underexplored. This study aimed to assess this relationship to enhance prevention and treatment strategies for SP. A retrospective analysis was conducted on 325 SP patients from the Medical Information Mart for Intensive Care IV (MIMIC-IV) database. The patients were divided into four groups (Q1, Q2, Q3, Q4) based on ascending EOS levels. Baseline characteristics were analyzed to compare clinical indicators. Kaplan-Meier (K-M) survival analysis and weighted multivariate logistic regression models were employed to examine the association between EOS and SP. Additionally, univariate Cox regression analysis iden

SUBMITTER: Fan J 

PROVIDER: S-EPMC12569275 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature