App-based multimodal lifestyle-intervention for essential hypertension (HYPE): a decentralized randomised controlled trial.

ABSTRACT:

Background

Life-style interventions are effective in lowering blood pressure (BP) and reducing cardiovascular risk, but implementation is poor. We aimed to evaluate the efficacy of an app-based multimodal lifestyle intervention in reducing BP in patients with uncontrolled hypertension.

Methods

In a decentralized, single-blinded, randomized-controlled trial, adults with uncontrolled hypertension by home BP measurement were randomized to 12 weeks of app-based multimodal lifestyle intervention or care as usual. The primary outcome was the difference of mean systolic BP after 12 weeks. Secondary outcomes were mean diastolic BP difference, and changes in body weight, health-related quality of life, and food literacy. An intention-to-treat analysis with multiple imputation by chai

SUBMITTER: Beger C 

PROVIDER: S-EPMC12569480 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature