The effect of <i>Withania somnifera</i> (Ashwagandha) on mental health symptoms in individuals with mental disorders: systematic review and meta-analysis.

ABSTRACT:

Background

Withania somnifera (WS) is considered an adaptogen agent with reported antistress, cognition facilitating and anti-inflammatory properties, which may be beneficial in the treatment of mental disorders.

Aims

This systematic review investigated the efficacy and tolerability of Withania somnifera for mental health symptoms in individuals with mental disorders.

Method

The protocol of this review was registered with PROSPERO (CRD42023467959). PubMed, Scopus, PsycINFO, CINAHL, Embase and CENTRAL were searched for randomised controlled trials comparing Withania somnifera to any comparator, in people of any age, with any mental disorder. The meta-analyses were based on standardised mean differences (SMDs) and odds ratios with 95% confidence int

SUBMITTER: Marchi M 

PROVIDER: S-EPMC12569615 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature