Obstructive Sleep Apnea and Cerebral Microbleeds in Middle-Aged and Older Adults.

ABSTRACT:

Importance

The association of obstructive sleep apnea (OSA) with risk of incident cerebral microbleeds (CMBs) is unknown.

Objective

To investigate the association between OSA severity and risk of incident CMBs in the late middle-aged general population.

Design, setting, and participants

This cohort study included eligible participants who had in-home overnight polysomnography data and brain magnetic resonance imaging done at baseline (2011-2014) and 4-year follow-ups (first follow-up, 2015-2018, and second follow-up, 2019-2022) from an ongoing longitudinal cohort study of a Korean community of adults. Data were analyzed from March 2024 through January 2025.

Exposures

OSA severity was categorized by apnea-hypopnea index levels as no OSA (0-4.9 events/h), mild OS

SUBMITTER: Siddiquee AT 

PROVIDER: S-EPMC12569715 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature