Initial motility and vitality predict the semen quality after long-term cryostorage, even in patients with restricted ejaculate parameters.

ABSTRACT:

Background

Cryopreservation of human semen is the cornerstone for preserving male fertility before gonadotoxic therapy or in cases of high variability in semen parameters. This is particular crucial in cases of severe oligoasthenoteratozoospermia (OAT), where diminished sperm counts may compromise planned intracytoplasmic sperm injection (ICSI) procedures. Previous investigations in donor programs have shown long-term storage effects, such as decreased motility in cryopreserved semen samples. However, these studies were based on patients exhibiting normozoospermic semen samples. To date, there has been no comprehensive evaluation of the effect of long-term cryostorage on sperm samples from individuals with compromised semen parameters.

Objectives

The aim of this study was to

SUBMITTER: Bier S 

PROVIDER: S-EPMC12569725 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature