Testing an interpersonal risk pathway to suicidal ideation in adolescence: linking neural, psychological, and sociometric indices of socially relevant factors.

ABSTRACT: Sensitivity to the social environment is linked to suicidal ideation in adolescence, and little research has examined variance in neural functioning that may underlie this sensitivity and increase risk. Neural-based pathways to suicidal ideation are likely mediated by subjective experiences of the social environment. Loneliness is associated with both salience network connectivity and suicidal ideation. This longitudinal study tested whether greater salience network functional integration (i.e. global efficiency) in early adolescence, which may underlie hypervigilance to social experiences, predicts risk for future suicidal ideation via loneliness. Participants (N = 96; Mage=12.94) completed a fMRI scan to measure resting-state salience network functional integration. Loneliness, suicidal

SUBMITTER: Pollak OH 

PROVIDER: S-EPMC12569756 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature