Efficacy and safety of remimazolam for sedation during gynaecologic procedures: a systematic review and meta-analysis.

ABSTRACT:

Introduction

The efficacy of remimazolam compared to propofol for sedation during gynaecologic procedures remains unknown, due to the increased severity of pain associated with these procedures. Therefore, a systematic review and meta-analysis was conducted to address this issue.

Materials and methods

The protocol has been registered with PROSPERO, number CRD42024511475. Medline/PubMed, Cochrane Library, Embase, Scopus and Web of Science were searched to identify randomized controlled trials (RCTs) covering the period up to 10 January 2025. The primary outcomes comprised the success rate of sedation and the incidence of body movement. Secondary outcomes included recovery time and incidence of adverse effects (i.e. hypotension, bradycardia, respiratory depression, postoperati

SUBMITTER: Yu G 

PROVIDER: S-EPMC12570234 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature