Recent advances in theranostic nanomaterials for overcoming traumatic brain injury.

ABSTRACT: Traumatic brain injury (TBI) is a major global health challenge characterized by complex secondary injury mechanisms involving oxidative stress, inflammation, and blood-brain barrier (BBB) disruption. Traditional biosensing and therapy strategies often face limitations due to ineffective biomarker detection and poor drug targeting at the injury site. Recently, theranostic nanomaterials have emerged as a promising solution, integrating diagnostic and therapeutic functionalities within a single nanoscale platform. This review explores the latest advances in nanotherapeutics and nanosensors for TBI management. The first section summarizes various nanotherapeutic approaches, including PEGylated-polystyrene nanoparticles, porous silicon nanoparticles, carbon dot nanoparticles, dendrimer nanopar

SUBMITTER: Hwang NC 

PROVIDER: S-EPMC12570421 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature