Carbon source-dependent transcriptomic regulation and monosaccharide remodeling of exopolysaccharide biosynthesis in Pediococcus pceusentosa LL-07.

ABSTRACT:

Background

Exopolysaccharides (EPSs) produced by lactic acid bacteria (LAB) play important roles in industrial applications. The type of carbon source affects both the production and composition of EPSs. However, the molecular mechanisms underlying this regulation in Pediococcus pentosaceus remain poorly understood. This study explores the effects of different carbon sources on the EPS biosynthesis pathway and monosaccharide composition in P. pentosaceus LL-07, with particular emphasis on transcriptional regulation.

Results

EPS yields were similar under glucose, fructose, or lactose (p > 0.05). However, RNA-Seq revealed distinct gene expression patterns. KEGG and GO analyses showed activation of carbohydrate metabolism and EPS-related pathways. Lactose significantly upregula

SUBMITTER: Lu K 

PROVIDER: S-EPMC12570439 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature