Comparative genomics of endemic <i>Staphylococcus aureus</i> ST1 in New Zealand.

ABSTRACT: Staphylococcus aureus is a major zoonotic bacterial pathogen that causes a broad spectrum of human and animal diseases, including skin infections, sepsis, endocarditis, and bovine mastitis. In the geographically isolated setting of New Zealand, the population structure of S. aureus exhibits a distinct genomic profile. Globally, bovine S. aureus isolates are primarily associated with sequence types (STs), ST97 and ST151, whereas in New Zealand, ST1 predominates, accounting for approximately 70% of bovine isolates. ST1 is also a clinically significant sequence type in humans. This study employed a comparative One Health approach to investigate genetic differences in 520 S. aureus ST1 isolated from bovine milk and human clinical samples. We aimed to explore genomic

SUBMITTER: Voss EM 

PROVIDER: S-EPMC12570506 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature