Triglyceride-glucose index, a silent predictor for osteosarcopenic adiposity occurrence and risk of cardiovascular and all-cause mortality.

ABSTRACT:

Background

The evidence linking the triglyceride-glucose (TyG) index to osteosarcopenic adiposity (OSA) in young and middle-aged populations is limited. This study aimed to investigate the association between the TyG index and OSA, and to determine the predictive value of the TyG index for all-cause and cardiovascular disease (CVD) mortality in OSA patients.

Methods

This cross-sectional and cohort study enrolled 8,098 participants aged 20-59 in the National Health and Nutrition Examination Survey (1999-2006 and 2011-2018). Mortality was determined by linkage to the National Death Index through December 31, 2019. Multivariable logistic regression models and restricted cubic splines (RCS) were constructed to determine the association between the TyG index and the prevalence of

SUBMITTER: Shao X 

PROVIDER: S-EPMC12570642 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature