Synchronous quantification of arterial, venous, and cerebrospinal fluid flow dynamics using real-time phase-contrast MRI.

ABSTRACT:

Background

Neurofluid flow dynamics are frequently studied from asynchronous blood and CSF flow measurements from real-time imaging using separate phase contrast (PC) MRI scans. Asynchronous measures can be influenced by changes in heart rate, respiration, and other physiological processes, obfuscating neurofluids assessment. Here we present an approach for synchronous measures of neurofluids using simultaneous real-time 2D PC MRI and investigated the effects of different breathing patterns on synchronous and asynchronous blood and CSF flow in a group of healthy participants.

Methods

Interleaved dual-velocity encoding 2D PC MRI with retrospective real-time reconstruction was utilized for synchronous neurofluid measures during free breathing, paced breathing and breath holds.

SUBMITTER: Rivera-Rivera LA 

PROVIDER: S-EPMC12570739 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature