Epidemiological trends of osteoarthritis at the global, regional, and national levels from 1990 to 2021 and projections to 2050.

ABSTRACT:

Background

Osteoarthritis is a major cause of disability worldwide, and understanding epidemiological trends in osteoarthritis is critical for public health planning and intervention strategies.

Methods

This study analyzed the global, regional, and national burden on osteoarthritis utilizing the Global Burden of Disease Study 2021. Trends from 1990 to 2021 were primarily assessed, with projections to 2050 based on demographic changes and historical data.

Results

In 2021, 607 (95% UI: 538-671) million people worldwide suffered from osteoarthritis, including 46.6 (95% UI: 41.1-51.6) million new cases, and the DALYs was 21.3 (95% UI: 10.2-42.9) million. Age-standardized incidence, prevalence and DALYs rates increased to 535.00/100,000 (95% UI: 472.38-591.97), 6967.29/100

SUBMITTER: Qiao L 

PROVIDER: S-EPMC12570834 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature