Association between normal systolic blood pressure maintenance and the risk of coronary artery calcification progression in asymptomatic non-diabetic and diabetic adults: a retrospective cohort study using data from the Korea initiatives on coronary artery calcification registry.

ABSTRACT:

Objectives

To assess the association of normal systolic blood pressure maintenance (SBP_maintain) with coronary artery calcification (CAC) progression in non-diabetic and diabetic subjects at low to intermediate cardiovascular risk.

Design

Retrospective cohort study with a mean follow-up of 3.3 years.

Setting

Data from the Korea Initiatives on Coronary Artery Calcification registry were analysed.

Participants

10 754 asymptomatic Korean adults (51.5±8.6 years; 84.5% male; 14.2% diabetes) were enrolled. Participants were divided into two groups: normal SBP_maintain (<120 mmHg) and ≥elevated SBP_maintain (≥120 mmHg) at the time of follow-up CAC scan.

Main outcome measures

CAC progression was defined as a difference of ≥2.5 betw

SUBMITTER: Won KB 

PROVIDER: S-EPMC12570917 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature