Gender differences in clinical features, comorbidities and prognostic outcomes in idiopathic pulmonary fibrosis-a retrospective cohort analysis from the British Thoracic Society Interstitial Lung Disease Registry.

ABSTRACT:

Background

Idiopathic pulmonary fibrosis (IPF), an unknown aetiology type of interstitial lung disease (ILD), carries the poorest prognosis and is more common in males and the elderly. Gender differences in baseline presentation, lung function and comorbidities may have an impact on prognostic outcomes.

Objective

The aim of this study was to explore gender differences in clinical features, comorbidities and outcomes in IPF in a UK cohort.

Method

This was a retrospective cohort study analysing data from the British Thoracic Society UK IPF ILD Registry from January 2013 to February 2024. We compared baseline characteristics between males and females, and a survival analysis in both genders was performed using the Cox proportional hazards model.

Results

We identif

SUBMITTER: Sia LC 

PROVIDER: S-EPMC12570927 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature