Right Atrial Contraction Strain Is Associated With Clinically Significant Cellular Rejection in Patients After Heart Transplantation.

ABSTRACT: Strain echocardiography (SE) may be used for surveillance in patients after heart transplantation (HTx); however, data on atrial strain are lacking. We aimed to compare the significance of ventricular and atrial strain with respect to an associated acute cellular rejection (ACR). Patients who underwent an endomyocardial biopsy (EMB) within 1 year after HTx were eligible for this retrospective analysis. The relationship between SE and ACR was assessed. EMB results of 52 patients (median age, 53 years; 63% male) at a median of 181 days post-HTx were identified. Mild ACR was present in 19 patients and ≥ moderate ACR in 6 patients. ACR ≥ moderate was associated with right ventricular free wall strain (OR 1.20, 95%CI 1.02-1.46, P = 0.04) and right atrial contraction strain (RASct; OR 1.55, 95%C

SUBMITTER: Rieth AJ 

PROVIDER: S-EPMC12571671 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature