Implementation of blood culture stewardship during a blood culture bottle shortage: a multicenter assessment.

ABSTRACT:

Objective

Assess clinical outcomes, knowledge, and attitudes about shortage mitigation interventions during a nationwide blood culture bottle shortage. We hypothesized that efforts to target ordering of blood cultures would not change patient-oriented outcomes.

Design

Retrospective, noninferiority, multicenter study.

Setting

Tertiary, rural healthcare system.

Patients

Eligible patients had any culture ordered before and after mitigation strategies.

Interventions

Mitigation strategies were rapidly implemented to preserve the availability of blood culture bottles for high-risk patients. Interventions included best practice advisories, algorithms, cascade questions, hard stops, education, and communication.

Results

The primary composite outcome (deat

SUBMITTER: Sevilla K 

PROVIDER: S-EPMC12571678 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature