Genomic diversity, antimicrobial resistance and dissemination of <i>Serratia marcescens complex</i> in patients admitted to ICUs.

ABSTRACT:

Background

Serratia spp. is an important nosocomial pathogen, with increasing threat of antimicrobial resistance. We aimed to describe the population structure, antimicrobial resistance and dissemination of Serratia isolates in ICUs of China.

Methods

Serratia spp. were isolated from patients admitted to ICUs of a large hospital between January 2014 and December 2024. Whole-genome and clinical data were collected to identify their epidemiological and evolutionary characteristics.

Results

106 Serratia isolates was divided into five species based on phylogenomic and ANI analyses, namely S. sarumanii, S. ureilytica, S. marcescens, S. bockelmannii, and S. nevei. The predominant ST was ST595 (12.3%), followed by

SUBMITTER: Zhu W 

PROVIDER: S-EPMC12571799 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature