Characterizing sleep-related phenotypes with patient-reported outcomes in Parkinson's disease.

ABSTRACT:

Objective

Sleep disturbances are common in Parkinson's disease (PD) and significantly impact patients' quality of life. However, the clinical symptoms associated with poor sleep remain underexplored. The Patient-Reported Outcomes in PD (PRO-PD) is a remote patient monitoring tool enabling symptom-level resolution. The goal of this study was to use the PRO-PD to describe symptomatic differences associated with sleep quality.

Methods

A cross-sectional analysis was conducted using baseline data of an ongoing prospective cohort study of patients with idiopathic PD (IPD). Sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI), while disease severity was evaluated using the PRO-PD. Multivariable regression analysis was performed to judge the association between

SUBMITTER: Grover S 

PROVIDER: S-EPMC12571807 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature