Association between C-reactive protein-triglyceride glucose index and abnormal BMD in middle-aged and elderly patients with type 2 diabetes mellitus: a cross-sectional study.

ABSTRACT:

Background and aims

Bone loss is an irreversible physiological change occurring with age. Type 2 diabetes mellitus (T2DM) is associated with poor bone health, and insulin resistance (IR) and inflammation are common pathologic mechanisms in T2DM and osteopenia/osteoporosis (OP). C-reactive protein-triglyceride glucose index (CTI), a novel marker of IR and inflammation, has been Investigated in various diseases. However, its potential association with the incidence of T2DM combined osteopenia/OP in T2DM remains unclear. This study aimed to investigate the association between the CTI and osteopenia/OP in middle-aged and elderly patients with T2DM.

Methods

This retrospective cross-sectional study analyzed 847 middle-aged and elderly patients with T2DM. The CTI was calculated as

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC12571813 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature