Portal vein hemodynamics measured by 4D flow MRI in predicting minimal hepatic encephalopathy in chronic hepatic schistosomiasis patients.

ABSTRACT:

Background

Minimal hepatic encephalopathy (MHE) is a subclinical neuropsychological disorder frequently observed in chronic hepatic schistosomiasis (CHS) patients. Early diagnosis is challenging due to the subtle and nonspecific nature of MHE symptoms. Advances in magnetic resonance imaging (MRI), specifically 4D flow MRI, allow for non-invasive evaluation of portal vein hemodynamic parameters, offering a potential tool for diagnosing MHE.

Objective

To evaluate the application of portal vein hemodynamic parameters measured by 4D flow MRI in diagnosing MHE in CHS patients.

Methods

This prospective observational study included 118 CHS patients, divided into MHE (n = 52) and non-MHE (n = 66) groups. Portal vein hemodynamic parameters, including peak velocit

SUBMITTER: Liu XF 

PROVIDER: S-EPMC12571824 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature