Pathogenic characteristics of an unencapsulated Streptococcus suis serotype 31 strain isolated from a patient in Thailand.

ABSTRACT: Streptococcus suis is a zoonotic pathogen that causes invasive infections in individuals who are in close contact with infected pigs or contaminated pork-derived products. An unencapsulated S. suis serotype 31 strain 43640 (sequence type 221) was first isolated from a human in Thailand in 2015; however, the mechanisms underlying host-cell interactions and virulence in animal models of this serotype are still limited. This study aimed to determine the virulence of the human unencapsulated S. suis serotype 31 strain 43640 using in vitro (A549 epithelial cells) and in vivo (C57BL/6 mouse) models. The adhesion rate of the unencapsulated strain 43640 to A549 cells was significantly lower than that of the highly pathogenic S. suis serotype 2 strain P1/7 after infection at multiplicity of infecti

SUBMITTER: Boueroy P 

PROVIDER: S-EPMC12572326 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature