Thromboembolic and cardiovascular risk profiles in patients with ulcerative colitis initiating advanced therapies.

ABSTRACT:

Background

Ulcerative colitis (UC) is associated with an increased risk of venous thromboembolism (VTE) and cardiovascular (CV) events, particularly during flares. While concerns have emerged regarding the intrinsic CV and thromboembolic risk of Janus kinase inhibitors, real-world data on baseline risk profiles in UC remain scarce.

Objectives

This study aimed to assess the thromboembolic and cardiovascular risk profiles of UC outpatients initiating advanced therapies and to evaluate the incidence of related clinical events.

Design

We conducted a cross-sectional study with prospective longitudinal follow-up at a single tertiary center.

Methods

Consecutive UC outpatients who initiated an advanced therapy between June 2020 and December 2023 were enrolled. Baseline

SUBMITTER: Calvez V 

PROVIDER: S-EPMC12572596 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature