Multiple-Branch Alcohol Septal Ablation Is Associated with Reduced Cardiovascular Events: Insights from a Trans-Pacific Multicentre Registry.

ABSTRACT:

Background

Alcohol septal ablation (ASA) is an established intervention for patients with drug-refractory obstructive hypertrophic cardiomyopathy. Whereas some patients require ASA with multiple target septal branches due to a residual pressure gradient, the prognostic effect of multiple-branch ablation remains unclear. Thus, we aimed to investigate the association of multiple-branch ablation with cardiovascular (CV) events after ASA.

Methods

This multicentre trans-Pacific study enrolled patients who underwent ASA at 4 institutions in the US and Japan. Patients were categorized into single- and multiple-branch ablation groups. CV events, defined as a composite of CV death, repeated septal reduction therapy, and heart failure hospitalization, were compared in 2 groups within

SUBMITTER: Akita K 

PROVIDER: S-EPMC12572884 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature