Asymptomatic Human Infections With Avian Influenza A(H5N1) Virus Confirmed by Molecular and Serologic Testing: A Scoping Review.

ABSTRACT:

Importance

Since 1997, more than 1000 infections with highly pathogenic avian influenza A(H5N1) virus among humans have been reported globally. Given ongoing A(H5N1) outbreaks in animals, understanding the frequency of A(H5N1) virus infections among asymptomatic persons can inform public health risk assessments and infection prevention guidance.

Objective

To identify and characterize reported cases of asymptomatic A(H5N1) virus infection among humans with confirmation by both molecular testing of 1 or more respiratory specimens and 1 or more serum specimens meeting World Health Organization criteria (molecularly and serologically confirmed [MSC]) or molecular confirmation (MC) alone.

Evidence review

MEDLINE, Embase, Global Health, Cochrane, Scopus, Virtual Health Libr

SUBMITTER: Dawood FS 

PROVIDER: S-EPMC12573033 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature