Liraglutide and Weight Loss Among Suboptimal Responders to Metabolic Bariatric Surgery: A Randomized Clinical Trial.

ABSTRACT:

Importance

Suboptimal weight loss after metabolic bariatric surgery (MBS) is a common indication for conversion surgery. The use of obesity management medications may improve weight loss, reducing the need for further surgery.

Objective

To examine whether liraglutide improves weight loss and health outcomes after MBS in patients who have had suboptimal weight loss.

Design, setting, and participants

This prospective, double-blinded, single-center randomized clinical trial compared the effect of daily liraglutide with placebo in adults treated at an academic surgical department. Patients with anatomically correct adjustable gastric band, sleeve gastrectomy, one anastomosis gastric bypass, or Roux-en-Y gastric bypass (confirmed with barium swallow and/or endoscopy) were

SUBMITTER: Brown WA 

PROVIDER: S-EPMC12573037 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature