Tuning Rheology and Printability of Gelatin Methacryloyl/Sodium Alginate Bioinks: The Role of Sodium Alginate Molar Mass and Sterilization.

ABSTRACT: Gelatin methacryloyl (GelMA)/sodium alginate (SA) bioinks are widely explored for various biomedical applications due to their favorable biocompatibility and tunable properties. However, the molar mass (MM) of SA, a critical factor influencing bioink properties, has not yet been systematically investigated in these systems. In this work, we highlight the importance of SA MM as a key parameter that governs the rheological behavior of GelMA/SA bioinks, directly impacting their printability and the structural and mechanical characteristics of the resulting hydrogels. Three types of SA used are characterized by very low (SA-VL), low (SA-L), and medium (SA-M) weight-average MM ranging between 38 and 260 kg·mol^-1. In addition, the variability in the MM of SA is included as a result of

SUBMITTER: Hajovska P 

PROVIDER: S-EPMC12573050 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature