Conduct problems are associated with accelerated thinning of emotion-related cortical regions in a community-based sample of adolescents.

ABSTRACT: Few studies have examined the association between conduct problems and cerebral cortical development. Herein, we characterize the association between age-related brain change and conduct problems in a large longitudinal, community-based sample of adolescents. 1,039 participants from the IMAGEN study possessed psychopathology and surface-based morphometric data at study baseline (M = 14.42 years, SD = 0.40; 559 females) and 5-year follow-up. Self-reports of conduct problems were obtained using the Strengths and Difficulties Questionnaire (SDQ). Vertex-level linear mixed effects models were implemented using the Matlab toolbox, SurfStat. To investigate the extent to which cortical thickness maturation was qualified by dimensional measures of conduct problems, we tested for an interaction bet

SUBMITTER: Albaugh MD 

PROVIDER: S-EPMC12573193 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature