Risk factors for recurrent attacks of wheeze in preschool children: a population-based cohort study in England.

ABSTRACT:

Objective

To determine factors associated with recurrent attacks of acute wheeze in preschool children.

Design

Retrospective cohort study.

Setting

English primary electronic health data from the Clinical Practice Research Datalink linked with hospital data from Hospital Episode Statistics.

Participants

42 820 children aged 5 years or under with at least one acute wheeze presentation between 1 January 2013 and 31 December 2014.

Exposures

Demographic and clinical variables including age, sex, ethnicity, deprivation quintile, clinical comorbidities and previous asthma medication prescriptions and acute attacks were included in multivariable analyses.

Main outcome measures

Further healthcare presentation with an acute wheeze/asthma attack within 12 mo

SUBMITTER: Lo D 

PROVIDER: S-EPMC12573339 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature