Protracted exposure to low-dose ionising radiation and cancer incidence among Canadian nuclear power plant workers.

ABSTRACT:

Objectives

Ionising radiation is a human carcinogen; however, there are uncertainties about the shape of the exposure-response function at low doses. We evaluated the relationship between radiation dose and cancer incidence in a cohort of Canadian nuclear power plant workers (NPPWs) with protracted exposures to low-dose ionising radiation.

Methods

The cohort included 75 350 workers employed at one of five Canadian nuclear power plants any time between 1945 and 2010. Exposure to cumulative whole-body effective dose was determined through personal monitoring. A total of 4370 incident cancers were identified through record linkage of these workers to national cancer registries (1969-2010). Vital status was determined through linkages to national mortality and tax databases. Sta

SUBMITTER: Hinton P 

PROVIDER: S-EPMC12573341 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature