Prevalence, spectrum and aetiology of valvular heart disease based on community echocardiographic screening transition from different altitudes in Yunnan, China.

ABSTRACT:

Background

The burden of valvular heart disease (VHD) is rising rapidly globally, accompanied by substantial geographical disparities. Although altitude may influence cardiovascular system, no community-based studies have yet explored altitudinal differences in VHD epidemiology.

Objective

This study aims to investigate the prevalence, spectrum and aetiology of VHD in different altitude areas.

Methods

We conducted two sequential community-based echocardiography screening programmes in Yunnan Province of China and included 5059 eligible participants aged 35 years and older. The multivariable Poisson regression models with robust variance were performed to assess the association of different altitude groups with VHD and its subtypes.

Results

The prevalence of over

SUBMITTER: Pang L 

PROVIDER: S-EPMC12573351 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature