Clinical characteristics and prognosis of pulmonary lymphoepithelioma-like carcinoma: a multicenter cohort study of 1106 cases.

ABSTRACT:

Background

Pulmonary lymphoepithelioma-like carcinoma (PLELC) is a rare form of squamous lung cancer with clinical features that have conflicting findings from different studies. Meanwhile, the survival time, pattern of failure after treatment, and independent prognostic factors of these patients need to be further confirmed by large-sample studies, and whether their treatment regimens need to be different from those of squamous lung cancer remains unknown.

Patients and methods

Patients with PLELC diagnosed by pathology from January 2009 to December 2023 at four medical centers in China were retrospectively analyzed.

Results

A total of 1106 patients with PLELC were enrolled in the study. Of these patients, 0.3% (3/1106) had brain metastasis, and 71.6% (176/204) tested

SUBMITTER: Hou Z 

PROVIDER: S-EPMC12573445 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature