Effect of pressure-controlled ventilation-volume guaranteed mode on intraoperative respiratory mechanics, oxygenation and postoperative pulmonary complications: a systematic review and network meta-analysis.

ABSTRACT:

Background

Ventilation strategies during general anesthesia are crucial for optimizing respiratory mechanics, ensuring adequate oxygenation, and minimizing postoperative pulmonary complications (PPCs) in surgical patients. This systematic review and network meta-analysis (NMA) aim to evaluate the effect of pressure controlled volume guaranteed ventilation (PCV-VG) in patients undergoing non-cardiothoracic surgery.

Methods

We selected randomized controlled trials (RCTs) to explore the effect of PCV-VG mode on intraoperative respiratory mechanics, oxygenation and PPCs in surgical patients published in English by searching PubMed, Embase, Web of Science, and the Cochrane from inception to May 2025. The primary outcome was dynamic lung compliance (Cdyn).

Results

Fourteen

SUBMITTER: Liu Z 

PROVIDER: S-EPMC12573580 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature