Predicting outcomes in patients with pulmonary hypertension using right ventricular global longitudinal strain versus tricuspid annular plane systolic excursion (TAPSE) and fractional area change: a retrospective analysis.

ABSTRACT:

Background

Pulmonary hypertension (PH) is a progressive clinical condition that eventually leads to right ventricular (RV) failure. RV function is the primary determinant of morbidity and mortality in patients with PH. RV global longitudinal strain (RVGLS) is a promising echocardiographic metric used to assess RV function in this setting. Our study aimed to compare the ability of RVGLS, tricuspid annular plane systolic excursion (TAPSE) and fractional area change (FAC) to predict adverse outcomes in patients with PH.

Methods

We retrospectively evaluated 315 patients with PH of diverse etiologies with 62% constitute of WHO group 2 disease, who were followed at the PH clinic at the University of Virginia, from March 2012 to December 2018. We included all adult patients who met

SUBMITTER: Alturaif N 

PROVIDER: S-EPMC12573895 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature