Renal cell carcinoma detection: a systematic review in diagnostic urinary biomarkers.

ABSTRACT:

Background

Renal cell carcinoma (RCC) accounts for 90% of all renal neoplasms and is often incidentally detected through unrelated imaging procedures. Differentiating between benign and malignant renal masses remains challenging using imaging alone. Urinary biomarkers may aid in this distinction, yet none are currently implemented in the clinic. Moreover, a comprehensive overview of urinary diagnostic biomarkers for RCC is lacking. Therefore, we aimed to systematically review and summarize existing literature on potential urinary biomarkers with diagnostic properties for RCC.

Methods

PubMed, Scopus and Web of Science were used for the identification of eligible studies evaluating urinary biomarkers in adults with sporadic RCC which reported diagnostic properties compared to

SUBMITTER: Kelly JF 

PROVIDER: S-EPMC12574123 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature