Reproducibility and precision of renal perfusion quantification with contrast enhanced ultrasound in critically ill patients: a prospective observational study.

ABSTRACT:

Objective

Contrast-enhanced ultrasound (CEUS) is a promising tool to assess renal microcirculation. However, its reproducibility has never been formally assessed. We aimed to assess the reproducibility and precision of CEUS measurements in critically ill patients.

Methods

We conducted an observational study in 20 critically ill patients in stable cardio-pulmonary condition. In group 1 (n = 10), to assess CEUS reproducibility, we performed three CEUS scans within a one-hour time frame in rigorously similar conditions and settings. In group 2 (n = 10), to assess the influence of ultrasound contrast agent rate, we performed two CEUS scans, one with standard settings and the second with a doubled ultrasound contrast agent rate. CEUS-derived parameters included relative blood vol

SUBMITTER: Ma H 

PROVIDER: S-EPMC12574292 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature