Early-Onset Neonatal Infection and Attention Deficit Hyperactivity and Autism Spectrum Disorder: A Nationwide Cohort Study.

ABSTRACT:

Background

Early-onset neonatal infections are among the most common neonatal diseases. However, the long-term outcomes of the infections are not well understood.

Objective

To study the association between early-onset neonatal infection and attention deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD).

Methods

A nationwide register-based cohort study was conducted, including near-term and term children born between 1997 and 2013 with follow-up until 2021. An early-onset infection was defined as an invasive bacterial infection occurring within the first week of life, including both physician-assigned diagnoses and positive bacterial cultures. ADHD and ASD were defined by diagnoses or prescriptions of relevant medication. Associations between sepsis

SUBMITTER: Andersen M 

PROVIDER: S-EPMC12574489 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature