Bilateral Enlarged Vestibular Aqueduct: Auditory, Genetic and Radiological Characterization, and Benefits of Cochlear Implants.

ABSTRACT:

Objective

The study aimed to describe the auditory phenotype of patients with bilateral enlarged vestibular aqueduct, including benefits of cochlear implantation, and to look for genotype-phenotype correlation.

Study design

Retrospective single-center study.

Setting

Tertiary adult reference center.

Methods

Fifty-eight patients were included. Evolution of pure tone and speech audiometry was analyzed. Cochlear size, vestibular aqueduct width, and endolymphatic duct and sac volume were assessed on both computed tomography scan and magnetic resonance imaging. Genetic explorations were documented, and genotype-phenotype correlations were explored. Outcomes after cochlear implant (CI) were analyzed.

Results

Hearing loss was diagnosed at 4 ± 4.0 years, being in

SUBMITTER: Vigouroux A 

PROVIDER: S-EPMC12574651 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature