An oxygenating colloidal bioink for the engineering of biomimetic tissue constructs.

ABSTRACT: Ensuring a sufficient oxygen supply is pivotal for the success of bioprinting applications since it fosters tissue integration and natural regeneration. Variation in oxygen concentration among diverse tissues necessitates the precise recreation of tissue-specific oxygen levels in imprinted constructs to support the survival of targeted cells. Although oxygen-releasing biomaterials, such as oxygen-generating microparticles (OMPs), have shown promise for enhancing the oxygen supply of microenvironments in injured tissues, whether this approach is scalable for large tissues and whether tissue-specific bioinks with varying OMP concentrations remain printable remain unknown. This study addresses this critical gap by introducing an innovative class of engineered oxygenated bioinks that combine c

SUBMITTER: Jeong SH 

PROVIDER: S-EPMC12574680 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature