Genomic characterization of eight novel Bartonella species from bats and ectoparasites reveals phylogenetic diversity and host adaptation.

ABSTRACT: Bats are recognized as hosts of diverse Bartonella species, and Bartonella are known agents of human disease. Here, we reported the isolation of 26 Bartonella strains belonging to eight distinct species from two bat species (Myotis laniger and M. adversus) and their ectoparasites (bat flies and bat mites) collected from Chongming County, Hubei Province, China. We obtained whole genome sequences of the bat-borne Bartonella spp. with second and third generation sequencing. The genome size of the bat-borne Bartonella spp. ranged from 1.39 to 1.98 Mb, with the GC content from 35.30%-38.92%. Phylogenetic analysis revealed that the bat-borne Bartonella spp. were divergent from currently known Bartonella spp., and the Average Nucleotide Identity (ANI) values were all below 95%, indicating that th

SUBMITTER: Wang WJ 

PROVIDER: S-EPMC12574864 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature