Analysis of transcriptome and metabolome characteristics of blood in yaks at different reproductive stages.

ABSTRACT: The reproductive physiology of yaks differs significantly from that of other cattle breeds due to late sexual maturity, low fecundity and short estrus time. How to improve the reproductive efficiency of yaks has become the main research content and goal of yak reproduction technology. In this study, we collected blood samples from adult female yaks (4-8 years old) during different reproductive periods, including the period of anestrus (Y-A), estrus (Y-E) and pregnancy (Y-P), and investigated the changes of RNA expression and steroid hormone levels in yaks during different reproductive periods by using RNA-seq and target metabolomics, and screened for the genes and regulatory pathways. DEGs such as PDK4, ALAS2, GLP1R, SLC25A39, PGAP6, FOS, CD36</

SUBMITTER: Kang Y 

PROVIDER: S-EPMC12575335 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature